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Benzyl N-[(2S)-5-(diaminomethylamino)-1-[[(2S)-4-fluoro-3-oxobutan-2-yl]amino]-1-oxopentan-2-yl]carbamate
- Development stage
- Unknown
- Modality
- Peptides, Small Molecules
01
Overview
Benzyl N‑[(2S)‑5‑(diaminomethylamino)‑1‑[[(2S)‑4-fluoro-3-oxobutan-2-yl]amino]–1–oxopentan–2–yl]carbamate is a synthetic, experimental small molecule with a peptide-like structure. It is also known as benzoyl‐arginine‐alanine‐methyl ketone. The compound contains a fluoro-substituted methyl ketone moiety and an ornithine-derived guanidinium group, suggesting it may act as an inhibitor of serine or cysteine proteases by mimicking peptide substrates and covalently modifying the active site. There are no approved indications or clinical trials for this compound, and it is not approved by any major regulatory agency[6][5][2].
- Other names
- Benzoyl-arginine-alanine-methyl ketonebenzyl N-((1S)-4-((diaminomethyl)amino)-1-(((2S)-4-fluoro-3-oxobutan-2-yl)carbamoyl)butyl)carbamatebenzyl N-[ (1S ) -4-[ ( diaminomethyl ) amino ] -1-{ [ ( 2S ) -4-fluoro -3 -oxobutan -2 - yl ] carbamoyl } butyl ] carbamate
02
Targets
PRSS1 (Trypsin family)
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